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KMID : 1084220150220030190
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Journal of Rheumatic Diseases
2015 Volume.22 No. 3 p.190 ~ p.194
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A Case of Eosinophilic Granulomatosis with Polyangiitis Presenting with Subarachnoid Hemorrhage and Mononeuritis Multiplex
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Oh Se-Hwan
Park Won
Kwon Seong-Ryul
Lim Mie-Jin
Joo Ko-woon
Lee Oh-Hyun
Lee Ha-Young
Oh Se-Yang
Jung Kyong-Hee
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Abstract
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Eosinophilic granulomatosis with polyangiitis (EGPA), previously called Churg-Strauss syndrome, is an anti-neutrophil cyto-plasmic antibody associated vasculitis, accompanied by asthma, hypereosinophilia, nonfixed pulmonary infiltrates, and sinusitis. Peripheral neuropathy is common in patients with EGPA; however, a few cases of EGPA with central nervous system (CNS) involvement have been reported. A 45-year-old female referred for right side weakness and posterior neck pain was diag-nosed as EGPA with subarachnoid hemorrhage and mononeuritis multiplex. She was effectively treated with a high dose gluco-corticoid, cyclophosphamide, and intravenous immunoglobulin. EGPA with CNS involvement is uncommon and causes sig-nificant morbidity and mortality. Therefore more rapid and accurate diagnostic evaluation may be required. EGPA should be considered in patients with neurological symptoms and hypereosinophilia.
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KEYWORD
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Churg-Strauss syndrome, Subarachnoid hemorrhage, Mononeuropathies
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